Cannabis use and trauma

Cannabis Use and Trauma:

• Traumatic experiences are linked to increased cannabis use and higher instances of cannabis use disorder (CUD).
• Veterans who use cannabis medicinally have a higher association with combat exposure and arousal in triggering situations.
• There is a strong association between heavy PTSD symptoms and CUD.
• CUD is more strongly associated with PTSD compared to other psychological disorders.
• Trauma and psychological symptoms are significant predictors for cannabis initiation and CUD.

Cannabis Use for Treatment:

• THC is not effective in treating emotion-regulation and anxiety-related symptoms.
• CBD weakens the emotional response to traumatic memories.
• Cannabinoids may assist with fear extinction and combating depression.
• Naboline is effective in decreasing PTSD nightmares.
• Further studies are needed to confirm the therapeutic potential of cannabinoids.

Cannabis Use and Sleep:

• THC reduces time to sleep but disrupts circadian rhythms.
• Synthetic THC shows similar tolerance effects.
• Higher CBD doses show potential therapeutic effects on sleep.
• CBD reduces sleep latency due to anxiety in REM sleep.
• CBD may help in managing sleep disturbances in individuals with PTSD and MDD.

Cannabis Use and Mental Health:

• Cannabis use is explored for its association with depression.
• Anxiolytic effects of cannabinoids, such as Delta9-tetrahydrocannabinol, are studied.
• Structural MRI findings in long-term cannabis users are examined.
• The role of the hippocampus in feedback regulation of stress responses is investigated.
• Delta9-tetrahydrocannabinol impacts brain temperature and circadian rhythms.

Studies on Synthetic Cannabinoids for PTSD Treatment:

• Various studies have explored the use of synthetic cannabinoids for managing PTSD symptoms.
• Synthetic cannabinoids have shown promise in addressing treatment-resistant nightmares in PTSD.
• Research has been conducted on the efficacy of nabilone and oral Δ9-tetrahydrocannabinol in treating PTSD-associated symptoms.
• These studies highlight the potential of synthetic cannabinoids in the treatment of PTSD-related symptoms.

Cannabis use and trauma Data Sources