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Tetrahydrocannabiphorol [THCP]

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Tetrahydrocannabiphorol (THCP) is a potent phytocannabinoid, a CB1 and CB2 agonist that was initially known as a synthetic homologue of THC, but was later isolated as a natural product in trace amounts from Cannabis sativa in 2019.

Isomers

  • Δ-THCP and Delta-3-THCP were both synthesized in 1941.
  • Both isomers have similar potency to Δ-THC.
  • Parahexyl is significantly stronger than both Δ-THCP and Delta-3-THCP.
  • JWH-091 (Δ-THCP) and Delta-3-THCP are synthetic cannabinoids.
  • JWH-091 has double the binding affinity at the CB receptor compared to Δ-THC.

Natural Occurrence in Cannabis

  • THCP occurs naturally in Cannabis in small amounts.
  • Analysis revealed THCP content in mid to high THC strains ranging from 0.0023% to 0.0136%.
  • There is no correlation between THC percentage and THCP content.
  • Some strains with 8% THC have similar THCP amounts to those with 20% THC.
  • Studies have identified THCP content in different Cannabis sativa accessions.

Delta-8-THCP

  • Delta-8-THCP is a code name for the Δ-isomer.
  • JWH-091 (Δ-THCP) is a synthetic cannabinoid.
  • Delta-8-THCP may be found naturally in cannabis plants.
  • JWH-091 has double the binding affinity at the CB receptor compared to Δ-THC.
  • Delta-8-THCP has higher binding activity than Δ-THC and Δ-THC.

Research Studies

  • Studies have identified THCP content in Cannabis sativa.
  • THCP content ranges from 0.0023% to 0.0136% in mid to high THC strains.
  • THCP content does not correlate with THC percentage.
  • Strains with different THC percentages can have similar THCP amounts.
  • Various research studies have analyzed the content of THCP in Cannabis sativa.

Tetrahydrocannabiphorol Data Sources

ReferenceURL
Glossaryhttps:/glossary/tetrahydrocannabiphorol
Wikipediahttps://en.wikipedia.org/wiki/Tetrahydrocannabiphorol
Wikidatahttps://www.wikidata.org/wiki/Q85806080
Knowledge Graphhttps://www.google.com/search?kgmid=/g/11j4y8fbl7
DBPediahttp://dbpedia.org/resource/Tetrahydrocannabiphorol
Product Ontologyhttp://www.productontology.org/id/Tetrahydrocannabiphorol