11-Hydroxycannabinol

11-Hydroxycannabinol (11-OH-THC) is a metabolite of tetrahydrocannabinol (THC) that is produced in the liver. It is more potent than THC and has been shown to have psychoactive effects. 11-OH-THC is believed to contribute to the overall effects of cannabis consumption.

Similar Compounds

• 11-Hydroxyhexahydrocannabinol
• 11-Hydroxy-THC
• 11-Hydroxy-Delta-8-THC
• Cannabinodiol

Research References

• Yamamoto I, Kuzuoka K, Watanabe K, Narimatsu S, Yoshimura H (1988): Metabolic formation and pharmacological effects of 11-hydroxycannabinol, an active metabolite of cannabinol
• de A Leite J, de Oliveira MV, Conti R, de S Borges W, Rosa TR, Filgueiras PR, Lacerda V, Romão W, Neto ÁC (September 2018): Extraction and isolation of cannabinoids from marijuana seizures and characterization by 1H NMR allied to chemometric tools
• Yamamoto I, Watanabe K, Kuzuoka K, Narimatsu S, Yoshimura H (May 1987): The pharmacological activity of cannabinol and its major metabolite, 11-hydroxycannabinol
• Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanus L, et al. (September 1997): Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase

Cannabinoid Receptor Activity

• Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanus L, et al. (September 1997): Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase

11-Hydroxycannabinol Data Sources